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AccuDx CQ IL-6 (25 Test)
₹23,000.00
Overview
Buy IL-6 Fast Test Kit (Immunofluorescence Assay) used for determination of
Interleukin 6 (IL-6)
in human serum, plasma, whole blood and peripheral blood samples. IL-6 is an early maker in acute inflammation and this test can be used as an aid in the inflammatory diseases.
Interleukin 6 is a cytokine that functions in inflammation and maturation of B calls. Interleukin 6 functions: primely produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response.
50 in stock
About
IL-6 Fast Test Kit (Immunofluorescence Assay) is indented for in vitro quantitative determination of Interleukin 6 (IL-6) in human serum, plasma, whole blood and peripheral blood samples. IL-6 is an early maker in acute inflammation and this test can be used as an aid in the inflammatory diseases.
Summary:
IL-6 is a cytokine that functions in inflammation and maturation of B calls. The protein is primely produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response. This classical responsiveness to IL-6 is governed by a receptor complex consisting of two membrane-bound subunits, an 80 Da cognate Alpha-chain (IL-6R Alpha), and a ubiquitously expressed 130-KDa Beta-chain receptor (gp130) which acts as the universal signal transducing element for all IL-6 family cytokines.
Many different cells are capable of IL-6 synthesis including monocytes/macrophages, fibroblasts. endothelial cells, keratinocytes, mast cells. T cells and many tumor cell lines. In vivo and in vitro, IL-6 acts as a differentiation factor for B cells and an activation factor for T cells [L-6 is a patent growth factor of different human myelomas and is active in concentration less than 10 pg/mL. IL-3 and IL-6 show in vitro synergistic effects in the differentiation of hematopoietic progenitor cells.
Elevated IL-6 serum or plasma levels may occur in different diseases including sepsis, autoimmune diseases, lymphomas, AIDS, allomeric liver disease and in patients with infections, or transplant rejection.
Specification
The lest uses an anti-human IL-6 monoclonal antibody I configured with fluorescence latex coated on the junction of nitrocellulose membrane and sample pad, and another anth-human IL-6 monoclonal antibody I coated on the test line.
After the sample has been applied to the test trip, the fluorescence late labelled anti-human IL-6 antibody I binds with the IL-6 in sample and forms marked antigen-antibody complex is captured on the lest line by anti-human IL-6 antibody Il.
The fluorescence intensity of test ine increases in proportion to the amount of IL-6 in sample.
Then insert lest card into AccuDx CQ Immunofluorescence Quantitative Analyzer/automatically inserted by AccuDx CO Immunofluorescence Quantitative Analyzer (hereafter referred to as AccuDx CO).
The concentration of IL-6 in sample will be measured and disclaved on the screen. The value will be stored in AccuDx CQ and available lor downloading. The result can be easily transmitted to the laboratory or hospital information system.
Safety Information
- For in vitro diagnostic use only.
- Do not use the kit beyond the expiration date.
- Do not use the test card if the foil pouch is damaged.
- Do not open pouches until ready to perform the test.
- Do not reuse the test card.
- Do not reuse the pipet.
- Handle al specimens as potentially infectious. Proper handing and disposal methods should be followed in accordance with local regulations.
- Carefully read and follow user manual to ensure proper test performance.
Direction for Use
• Collect specimens according to user manual.
• Test card, sample and reagent should be brought to room temperature before testing.
For AccuDx CQ:
• Confirm SD card lot No. in accordance with test kit lot No..
• Perform “”SD card’ calibration when necessary.
• Enter testing interface of AccuDx CQ.
• Remove the test card from the sealed pouch immediately before use. Label the test card with patient or control identification.
• Put the test card on a clean table, horizontally placed.
• Using sample transfer pipette, deliver 100 L of sample into the sample port on the test card (for whole blood sample, one drop of whole blood butter must be added after loading 100 L on test card).
• Reaction time: 15 minutes. Insert the test card into AccuDx CO and start test after reaction time is elapsed. The result will be shown on the screen and printed automatically.
• Cormican Sarah. Griffin Matthew D. The Complex Role of Interleukin 6 in Regulating T-cell Responses during Acute Glomerulonephritis. Journal of the American Society of Necrology: JASN. 2019. 30 (B).
• Simondurairaj C, Krishnakumar R. Sundaram Sandrya, et al. Interleukin-6 Receptor (IL-GR) Expression in Human Gastric Carcinoma and its Clinical Signilicance. Cancer investigation, 2019, 37 (7).
• Barney Thaddeus M, Vore Andrew S. Garo Anny, Monder la Jamie E, et al. The influence of central interleukin- on behavioral changes associated with acute alcohol intoxication in adult male rats. Alcohol (Fayetteville, N.Y.). 2019. 79.
Other Info
- Store the test card at 4-30°C with a valid period of 24 months.
- Use the lest card within 1 hour once the foil pouch is opened.
- For test card of AccuDx CQ: if the cartridge is opened, it could be stable within 24 hours once exposed to air.
- If the test cards can’t be used up at a time, please put the cartridge back to the foil pouch and reseal along the entire edge of zip-seal.
- The remaining test cards should be used up within 7 days.
- Store the sample diluent at 0-30°C with a valid period of 24 months.
- Store the sample diluent at 2-B°C lor better results
Rahul S. –
Accurex is the old brand and trusted company in India